Dutch HIV-ziekte, humaan immunodeficiëntievirusinfectie, niet-gespecificeerd, HIV-infectie NAO, humaan immunodeficiëntievirussyndroom, HIV-ziekte; aandoening (als gevolg), HIV-ziekte; infectie, Humaan Immunodeficiëntievirus; ziekte, aandoening; HIV-ziekte (als gevolg van HIV-ziekte), aandoening; als gevolg van HIV-ziekte, immunodeficiëntievirus-ziekte; humaan, infectie; HIV-ziekte als oorzaak, Niet gespecificeerd ziekte door Humaan Immunodeficiëntievirus [HIV], HIV-infectie, HIV-infecties, HTLV-III-LAV-infectie, HTLV-III-infectie, Infecties, HIV-
A few exceptional patients can control their HIV strain without treatment; they maintain normal CD4 counts and very low blood levels of HIV (long-term nonprogressors) or normal CD4 counts and undetectable blood levels of HIV (elite controllers). These patients may not require ART, but studies to determine whether treating them is helpful have not been done and would be difficult because there are few of these patients and they would likely do well not taking ART for long periods.
^ Jump up to: a b c Knoll B, Lassmann B, Temesgen Z (2007). “Current status of HIV infection: a review for non-HIV-treating physicians”. Int J Dermatol. 46 (12): 1219–28. doi:10.1111/j.1365-4632.2007.03520.x. PMID 18173512.
UNAIDS announced that 18.2 million people were on ART, including 910 000 children, double the number five years earlier. However, achieving increased ART access means a greater risk of drug resistance and the WHO released a report on dealing with this growing issue.99
Because live-virus vaccines are potentially dangerous for patients with severe immunosuppression, expert opinion should be sought when dealing with patients at risk of primary varicella; recommendations vary (see Human Immunodeficiency Virus (HIV) Infection in Infants and Children : Vaccination and Considerations for Use of Live Vaccines in Children With HIV Infection).
n a type of retrovirus that causes AIDS. Retroviruses produce the enzyme reverse transcriptase, which allows transcription of the viral genome onto the DNA of the host cell. It is transmitted through contact with an infected individual’s blood, semen, cervical secretions, cerebrospinal fluid, or synovial fluid. It infects T-helper cells of the immune system and results in infection with a long incubation period, averaging 10 years.
HIV is a very small virus that contains ribonucleic acid (RNA) as its genetic material. When HIV infects animal cells, it uses a special enzyme, reverse transcriptase, to turn (transcribe) its into DNA. (Viruses that use reverse transcriptase are sometimes referred to as “retroviruses.”) When HIV reproduces, it is prone to making small genetic mistakes or mutations, resulting in viruses that vary slightly from each other. This ability to create minor variations allows HIV to evade the body’s immunologic defenses, essentially leading to lifelong infection, and has made it difficult to make an effective vaccine. The mutations also allow HIV to become resistant to antiretroviral medications.
Jump up ^ Garcia JV, Miller AD (April 1991). “Serine phosphorylation-independent downregulation of cell-surface CD4 by nef”. Nature. 350 (6318): 508–11. Bibcode:1991Natur.350..508G. doi:10.1038/350508a0. PMID 2014052.
Jump up ^ “Guidelines for the Use of Antiretroviral Agents in HIV-1-Infected Adults and Adolescents” (pdf). Department of Health and Human Services. February 12, 2013. p. i. Archived (PDF) from the original on November 1, 2016. Retrieved January 3, 2014.
HIV infection occurs when particular body fluids (blood, semen, vaginal fluid and breast milk) containing the virus come into contact with another person’s tissues beneath the skin (for example, though needle puncture or broken skin), or mucous membranes (the thin moist lining of many parts of the body such as the nose, mouth, throat and genitals).
DHHS Panel on Antiretroviral Guidelines for Adults and Adolescents. “Guidelines for the Use of Antiretroviral Agents in HIV-1 Infected Adults and Adolescents.” Washington D.C.: Department of Health and Human Services, 2017.