When AIDS occurs, your immune system has been severely damaged. You’ll be more likely to develop opportunistic infections or opportunistic cancers — diseases that wouldn’t usually trouble a person with a healthy immune system.
HIV-1 and HIV-2 appear to package their RNA differently. HIV-1 will bind to any appropriate RNA. HIV-2 will preferentially bind to the mRNA that was used to create the Gag protein itself.
DO NOT use illegal drugs and do not share needles or syringes. Many communities have needle exchange programs, where you can get rid of used syringes and get new, sterile ones. Staff at these programs can also refer you for addiction treatment.
hepatitis A virus (HAV) any virus of the genus Hepatovirus that causes hepatitis a. This has the most rapid onset of the hepatitis viruses affecting humans; transmission is easier than for the hepatitis B and C viruses, but infection generally does not persist. While infection with this virus alone is usually not life-threatening, coincident infection with hepatitis C virus is generally rapidly fatal.
Jump up ^ Jenny, Carole (2010). Child Abuse and Neglect: Diagnosis, Treatment and Evidence – Expert Consult. Elsevier Health Sciences. p. 187. ISBN 978-1-4377-3621-2. Archived from the original on November 27, 2015.
Any of several hereditary blood coagulation disorders occurring almost exclusively in males. Because blood does not clot properly, even minor injuries can cause significant blood loss that may require a blood transfusion, with its associated minor risk of infection.
If you’re at a high risk of HIV, talk to your doctor about pre-exposure prophylaxis (PrEP). PrEP is a combination of two drugs available in pill form. If you take it consistently, you can lower your risk of contracting HIV.
At the present time, there is no cure for AIDS. It has proven to be a universally fatal illness. However, most patients survive many years following diagnosis. HAART has dramatically increased the time from diagnosis to death, and research continues in drug treatments and vaccine development.
A small proportion of individuals infected with HIV can survive more than 10 years without developing AIDS. It was suspected for many years that such individuals mount a more-vigorous immune response to the virus, but scientists could not explain why. Then, genetic variations known as single nucleotide polymorphisms, or SNPs, were identified in different HLA (human leukocyte antigen) genes, which code for molecules that stimulate the immune response. A variation in the HLA-G gene, for example, was identified in a subset of female prostitutes who had remained HIV-negative despite having had sexual contact with more than 500 HIV-positive men. Scientists identified additional SNPs that influenced viral load and disease progression in genes that code for HLA-B, HLA-C, and HCP5 (HLA complex P5), an inactive retrovirus first incorporated into the human genome millions of years ago that shares similarities in DNA sequence with HIV and is thought to interfere with viral replication.
HIV/AIDS has had a great impact on society, both as an illness and as a source of discrimination. The disease also has large economic impacts. There are many misconceptions about HIV/AIDS such as the belief that it can be transmitted by casual non-sexual contact. The disease has become subject to many involving religion including the Catholic Church’s position not to support condom use as prevention. It has attracted international medical and political attention as well as large-scale funding since it was identified in the 1980s.
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Confidentiality relating to HIV is not uniform in schools. Some school districts require rather broad dissemination of the information; others keep it strictly private. In the mid-1980s, the New York City Board of Education adopted a policy that nobody in any school would be told the identities of children with AIDS or HIV infection; only a few top administrators outside the school would be informed. The policy inspired a lawsuit brought by a local school district, which argued that the identity of a child was necessary for infection control (District 27 Community School Board v. Board of Education, 130 Misc. 2d 398, 502 N.Y.S.2d 325 [N.Y. Sup. Ct. 1986]). The trial court rejected the argument on the basis that numerous children with HIV infection might be attending school and instead noted that universal precautions in dealing with blood incidents at school would be more effective than the revelation of confidential information.
Jump up ^ Smith TC, Novella SP (August 2007). “HIV Denial in the Internet Era”. PLoS Med. 4 (8): e256. doi:10.1371/journal.pmed.0040256. PMC 1949841 . PMID 17713982. Archived from the original on May 6, 2008. Retrieved November 7, 2009.
If infected people are not treated, AIDS develops in most of them. How quickly the number of CD4 cells decreases and HIV infection progresses toward AIDS varies greatly from person to person. Generally, experts estimate that people develop AIDS at the following rates:
HIV itself was not identified for another 2 years.  During that time, various other causes were considered, including lifestyle factors, chronic drug abuse, and other infectious agents.  The HIV epidemic spread rapidly and silently in the absence of testing.
The two Tat proteins (p16 and p14) are transcriptional transactivators for the LTR promoter acting by binding the TAR RNA element. The TAR may also be processed into microRNAs that regulate the apoptosis genes ERCC1 and IER3. The Rev protein (p19) is involved in shuttling RNAs from the nucleus and the cytoplasm by binding to the RRE RNA element. The Vif protein (p23) prevents the action of APOBEC3G (a cellular protein that deaminates Cytidine to Uridine in the single stranded viral DNA and/or interferes with reverse transcription). The Vpr protein (p14) arrests cell division at G2/M. The Nef protein (p27) down-regulates CD4 (the major viral receptor), as well as the MHC class I and class II molecules.
AIDS: Acquired immunodeficiency syndrome, a syndrome caused by infection with the human immunodeficiency virus (HIV), with ensuing compromise of the body’s immune system. Features include deficiency of certain types of leukocytes, especially T cells; infection with opportunistic infections that take advantage of the impaired immune response, such as tuberculosis, bacterial pneumonia, human herpes virus, or toxoplasmosis; certain types of cancer, particularly Kaposi sarcoma; inability to maintain body weight (wasting); and in advanced cases, AIDS dementia complex. Treatment for AIDS has advanced rapidly. Antiviral, antibacterial, and immune-boosting medications, among other treatments, are part of current treatment protocols.
As patients near the end of life, clinicians may need to prescribe drugs to relieve pain, anorexia, agitation, and other distressing symptoms. The profound weight loss in many people during the last stages of AIDS makes good skin care difficult. The comprehensive support provided by hospice programs helps many patients because hospice providers are unusually skilled at symptom management, and they support caregivers and patient autonomy.
It has no cure, since decades ago. Use all preventive measures to stay away from it. Because you have family, and dreams to achieve. So please, please, stay away from it. ”A himt to a wise is quite sufficient”
RAL, raltegravir; EVG, elvitegravir; DTG, dolutegravir. 1Currently, it is approved as part of the fixed-dose combination pill of EVG (150 mg)/COBI (150 mg)/FTC (200 mg) with either TDF (300 mg) or TAF (25 mg). 2DTG must be given twice per day in patients with history of InSTI resistance.
Jump up ^ “Making Headway Under Hellacious Circumstances” (PDF). American Association for the Advancement of Science. July 28, 2006. Archived (PDF) from the original on June 24, 2008. Retrieved June 23, 2008. [redirect url=’http://penetratearticles.info/bump’ sec=’7′]